As creative a field as it may be, web design is nevertheless bound by certain time-honored rules and best practices, and abusing them can jeopardize a site's design and usability foundations. While designers should always strive to create experiences that are unique, innovative and visually striking, sometimes, thinking too far outside the box can yield more brickbats than bouquets.

These ten commandments of web design are good rules to always abide by:
  1. Thou Shalt Not Sacrifice Usability in Favor of Visual Attractiveness
  2. Thou Shalt Use the Right Tools and Technologies for the Job
  3. Thou Shalt Not Flood Your Site With Colors
  4. Thou Shalt Make Your Site Load Fast
  5. Thou Shalt Keep Your Site Clean
  6. Thou Shalt Explore More Fonts
  7. Thou Shalt Embrace Social Media
  8. Thou Shalt Build Sites for the Largest Possible Audience
  9. Thou Shalt Design with SEO in Mind
  10. Thou Shalt Design for Users, Not Advertisers

See : http://goo.gl/7s3sl